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Otsuka America Pharmaceutical

Rockville, Maryland, United States
Ownership
Private
Employees
~45000
Development stage
Other
01

Overview

Otsuka America Pharmaceutical (OAPI) markets multiple FDA-approved drugs—such as aripiprazole (ABILIFY), brexpiprazole (REXULTI), and tolvaptan (JYNARQUE)—for CNS and nephrology indications. Its development pipeline includes candidates in Phase 1-3 for CNS, nephrology, autoimmune diseases, metabolic disorders, and infectious diseases[2][6]. JNT-517 has achieved clinical proof of concept for PKU; other assets include new therapies for ALS, autoimmune kidney disorders, and TB.

Therapeutic areas
ImmunologyCardiovascularPsychiatryInfectious DiseasesMetabolic DisordersNephrologyNeurology
Modalities
Small moleculeAntibodyAntisense oligonucleotideBiologicMonoclonal antibody
Industry
Biotech
02

Drug pipeline

4 assets

OPC-14523

Preclinical

3 more assets in the full pipeline.

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03

Partnerships

Lundbeck (co-development of brexpiprazole, aripiprazole)[2][10]Visterra (VIS171, VIS954 programs)[2]Ionis Pharmaceuticals (ulefnersen for FUS-ALS)[2]

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