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Otter Pharmaceuticals, a subsidiary of Assertio Holdings, markets approved pharmaceutical products, most notably clobazam (targeting the GABAA receptor) for Lennox-Gastaut syndrome and methotrexate (targeting DHFR) for autoimmune indications such as psoriasis. Clobazam is commercialized as Sympazan® oral film for adjunctive treatment of seizures in LGS; methotrexate is provided via the OTREXUP device for subcutaneous delivery in conditions including psoriasis. Both products are approved and sold in multiple markets.
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