Company intelligence / Profile preview

Ovid Therapeutics

New York City, New York, United Statespmc.ncbi.nlm.nih.gov ↗
Ownership
Public · OVID
Employees
~23
Development stage
Phase 1
01

Overview

Ovid Therapeutics has advanced several novel small molecule candidates into early clinical development targeting neurological diseases with high unmet need. OV329, a next-generation GABA aminotransferase inhibitor for treatment-resistant seizures, completed Phase 1 with topline data expected in mid-to-late 2025. OV350, the first KCC2 direct activator from their library, entered Phase 1 in Q1 2025 for psychosis associated with NSD/LBD. The oral KCC2 activator OV4071 will enter human studies in Q2 2026. The ROCK2 inhibitor program OV888/GV101 completed a successful Phase 1 trial and was set to begin a proof-of-concept study in CCM but this was paused pending further review after competitor results; additional neurovascular applications are being explored.

Therapeutic areas
PsychiatryNeurology
Modalities
Small molecules
Industry
Biotech
02

Drug pipeline

8 assets

OV835

Preclinical

7 more assets in the full pipeline.

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03

Partnerships

Graviton Bioscience Corporation – collaboration on ROCK2 inhibitors including OV888/GV101 for CCM and other neurovascular conditions.
04

Financials

Market cap
$513.3M
Total revenue
$733K
Enterprise value
$408.8M

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