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Owl Therapeutics has a diversified pipeline targeting brain health through supercharged microglia. Its lead asset OWL‑1410 is entering Phase 2 trials for moderate/severe TBI, supported by promising early clinical data. The company leverages generative AI to design novel drugs and partners with Gryphon Bio to develop diagnostic blood tests that improve trial success rates. Additional programs target related CNS indications including Alzheimer’s disease, post-traumatic epilepsy, and post-traumatic headache. Several earlier assets have been discontinued or are preclinical.
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