Company intelligence / Profile preview
Palleon Pharmaceuticals
Waltham, Massachusetts, United Statespalleonpharma.com ↗
- Ownership
- Private
- Employees
- ~75
- Development stage
- Preclinical
01
Overview
Palleon's lead candidate E‑602 has demonstrated proof of mechanism and dose-dependent immune activation as a monotherapy in the GLIMMER‑01 trial for solid tumors. The drug was well tolerated with no dose-limiting toxicities. E‑602 has advanced to Phase 2 trials for autoimmune diseases under a collaboration with Henlius. The company’s platforms enable novel glyco-immunology approaches to address resistance to first-generation immuno-oncology drugs and expand treatment options across cancer and autoimmunity
- Therapeutic areas
- OncologyImmunology
- Modalities
- Enzyme-antibody fusion proteins (glycan editing enzymes)Glycoimmune checkpoint inhibitors
- Industry
- Biotech
02
Drug pipeline
7 assets6 more assets in the full pipeline.
03
Partnerships
Henlius – collaboration on clinical development of E‑602 for autoimmune diseasePfizer Ventures – strategic investor with board representation
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