Company intelligence / Profile preview

Palleon Pharmaceuticals

Waltham, Massachusetts, United Statespalleonpharma.com ↗
Ownership
Private
Employees
~75
Development stage
Preclinical
01

Overview

Palleon's lead candidate E‑602 has demonstrated proof of mechanism and dose-dependent immune activation as a monotherapy in the GLIMMER‑01 trial for solid tumors. The drug was well tolerated with no dose-limiting toxicities. E‑602 has advanced to Phase 2 trials for autoimmune diseases under a collaboration with Henlius. The company’s platforms enable novel glyco-immunology approaches to address resistance to first-generation immuno-oncology drugs and expand treatment options across cancer and autoimmunity

Therapeutic areas
OncologyImmunology
Modalities
Enzyme-antibody fusion proteins (glycan editing enzymes)Glycoimmune checkpoint inhibitors
Industry
Biotech
02

Drug pipeline

7 assets

efgitasialase alfa

2

6 more assets in the full pipeline.

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03

Partnerships

Henlius – collaboration on clinical development of E‑602 for autoimmune diseasePfizer Ventures – strategic investor with board representation

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