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Papyrus Therapeutics

West Chester, Pennsylvania, United Statespapyrustherapeutics.com ↗
Ownership
Private
Development stage
Preclinical
01

Overview

Papyrus Therapeutics is developing first-in-class extracellular tumor suppressor therapies, with its lead candidate PYTX‑004 (a recombinant OPCML-Fc fusion) at the IND-enabling stage. The company’s approach targets over 50% of solid tumors and aims to overcome resistance seen with traditional RTK inhibitors by restoring normal RTK signaling at the cell surface. Clinical data generation is expected to begin in approximately two years. Early preclinical collaborations are ongoing with partners such as Oxford Biomedica and Targovax, exploring synergy with CAR-T and oncolytic virus platforms.[1][3][5][6]

Therapeutic areas
Oncology
Modalities
Recombinant protein therapeuticsFusion proteinsOncolytic virusesCAR-T cell therapies[5][7]
Industry
Biotech
02

Drug pipeline

3 assets

PYTX-004

Preclinical

2 more assets in the full pipeline.

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03

Partnerships

Oxford Biomedica (CAR-T collaboration)[5]Targovax ASA (oncolytic virus collaboration)[6]

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