Paragon Intellectual Properties

Paragon Therapeutics is a biotechnology company and drug discovery engine focused on engineering best-in-class biologics for inflammatory, autoimmune, and oncology indications. Founded by Fairmount, the company utilizes a proprietary platform to optimize antibody properties, such as half-life and potency, before spinning them off into independent, well-funded companies. Notable spin-outs include Apogee Therapeutics, Spyre Therapeutics, Oruka Therapeutics, and Jade Biosciences. Paragon's business model centers on rapid development of 'fast-follower' or 'next-generation' therapies that address limitations of existing blockbuster drugs. The company's internal R&D efforts continue to generate a robust pipeline of engineered antibodies targeting validated pathways with improved therapeutic profiles.