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Parvus Therapeutics is developing a novel class of disease-modifying therapeutics called Navacims that use pMHC nanomedicines to induce antigen-specific regulatory T cells in vivo. This approach aims to restore immune tolerance and reverse autoimmune disease without broad immunosuppression. The company has demonstrated efficacy in multiple animal models and is advancing several drug candidates through preclinical development into the clinic. No active clinical trials are currently registered on ClinicalTrials.gov as of January 2025.
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