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Paterna Biosciences is developing a first-in-class in vitro spermatogenesis platform to generate healthy sperm from adult testicular stem cells. The company has demonstrated the ability to keep adult sperm stem cells alive and replicating longer than any other lab. Their IVS technology aims to address the significant unmet need of male infertility, which accounts for about half of all failed IVF cycles globally. The company is currently in preclinical development with plans for early-phase clinical studies starting in 2025.
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