Company intelligence / Profile preview
Pathios Therapeutics
Abingdon/Milton Park, Oxfordshire, UK
- Ownership
- Private
- Development stage
- Phase 1
01
Overview
Pathios Therapeutics has advanced its lead program PTT‑4256—a first-in-class orally bioavailable small molecule inhibitor of GPR65—into early clinical development. Preclinical data show reversal of immunosuppression in the tumor microenvironment and single-agent anti-tumor efficacy in animal models. The company aims to address patients who do not respond to current immunotherapies by targeting the root cause of immune dysfunction within tumors.
- Therapeutic areas
- OncologyImmunologyNeurology
- Modalities
- Small molecules (GPR65 inhibitors)
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
St Vincent’s Institute (SVI) of Medical Research, MelbourneQueensland University of Technology (QUT), BrisbaneStrategic investment from Bristol Myers Squibb
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