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PathMaker Neurosystems

Boston, Massachusetts, United Statespmneuro.com ↗

Ownership: Private
Development stage: Phase 2

Overview

PathMaker’s MyoRegulator® device is the first non-invasive neuromodulation system for muscle spasticity in stroke patients and is being developed as a disease-modifying treatment for ALS. The company has completed pivotal clinical trials in Europe with positive results for post-stroke spasticity and has initiated two clinical trials in ALS, including a Department of Defense-funded CALM study at leading Boston hospitals. The MyoRegulator® platform has received FDA Breakthrough Device designation and CE Mark clearance was anticipated by 2023–2024. Early feasibility studies have shown safety and initial efficacy signals

Therapeutic areas: Neurology
Modalities: DeviceNon-pharmacological therapyNeuromodulation technology (specifically, multi-site direct current stimulation)
Industry: Therapeutic Medical Devices

Drug pipeline

1 asset

MyoRegulator

Phase 2

Indications: Amyotrophic lateral sclerosis, Post-stroke spasticity

Partnerships

Beth Israel Deaconess Medical Center (Harvard Medical School)Spaulding Rehabilitation HospitalU.S. Department of Defense / Congressionally Directed Medical Research Program

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