perForm Biologics

perForm Biologics is a private biotechnology company focused on developing next-generation bone morphogenetic protein (BMP) therapies for bone repair and regeneration. The company's lead technology, Osteogrow, utilizes recombinant human BMP6 (rhBMP6) delivered within an autologous blood coagulum carrier, which aims to overcome the limitations of existing BMP-2 and BMP-7 products, such as high dosage requirements and inflammatory side effects. perForm Biologics is advancing a pipeline of products, including Osteogrow-A and Osteogrow-C, for indications such as spinal fusion, high tibial osteotomy, and distal radial fractures. The company's approach leverages the unique properties of BMP6, which exhibits higher osteogenic activity and reduced inhibition by natural antagonists compared to other BMPs. perForm Biologics operates through strategic collaborations with academic and industrial partners, including the University of Zagreb and Genera Research, and has received significant support from the EU Horizon 2020 program.