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Perpetual Medicines has developed an AI-driven computational peptide drug discovery engine. As of early 2024, it has three major preclinical oncology programs targeting intracellular PPIs—an area where peptides offer unique advantages over small molecules or antibodies. The company also has preclinical efforts in autoimmunity and metabolic disease. No clinical results have been reported yet; the most advanced program is expected to enter clinical trials soon.
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