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PharmaXon is a biotechnology company focused on the discovery and development of small molecule therapeutics targeting the P2X7 receptor. The company's research centers on the role of purinergic signaling in neuroinflammation and its contribution to various central nervous system (CNS) and inflammatory disorders. PharmaXon's lead candidate, PX-17, is being developed for indications including neuropathic pain and treatment-resistant depression. The company aims to address significant unmet medical needs by modulating the P2X7 pathway to reduce the release of pro-inflammatory cytokines like IL-1β. PharmaXon was founded as a spin-off from the Institute of Experimental Medicine of the Hungarian Academy of Sciences.
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