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PhaseBio Pharmaceuticals

Malvern, Pennsylvania, United Statessfj-pharma.com ↗

Ownership: Private
Employees: ~60
Development stage: Phase 3

Overview

PhaseBio’s lead asset, bentracimab, reached late-stage clinical development for the rapid reversal of ticagrelor’s antiplatelet effects. The company also advanced pemziviptadil for pulmonary arterial hypertension but suspended its pivotal trial due to COVID-related challenges. PB6440 was in preclinical development for resistant hypertension. Bentracimab manufacturing had reached commercial scale validation prior to the company’s financial difficulties and bankruptcy proceedings.

Therapeutic areas: Cardiovascular
Modalities: Recombinant proteinsPeptides (including elastin-like polypeptide fusions)Monoclonal antibody fragments
Industry: Biotech

Drug pipeline

5 assets

froniglutide

4 more assets in the full pipeline.

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Partnerships

SFJ Pharmaceuticals – co-development and financing partnership on bentracimab, including transfer-of-assets provisions triggered by financial distress/bankruptcyManufacturing partners included BIOVECTRA Inc. and Berkshire Sterile Manufacturing

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