PhysioCue

PhysioCue was a Silicon Valley medical device and digital health company developing non-invasive therapeutic devices for hypertension and migraine/headache management. Its core approach used patented thermal neurostimulation applied near the carotid region to modulate the autonomic nervous system and lower blood pressure, alongside biosensor-based monitoring and a mobile app for headache tracking. Company materials and third-party profiles describe a handheld hypertension therapy device, a migraine/headache therapy device, and associated monitoring software. Available sources indicate the company was founded in 2013, raised venture backing from several early-stage investors, and later became inactive or out of business. PhysioCue appears to have operated as a therapeutic-device developer rather than a traditional drug-development biotech company.