Clinical trials
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XEN-D0501, a TRPV1 antagonist, completed two Phase 2a trials showing good tolerability in type 2 diabetes patients, enhanced insulin response, and reduced ANP biomarker. Phase 2a dose-escalation trial (PP-CT03) planned for obesity/type 2 diabetes; orphan drug designation for erythromelalgia; preclinical POC for abdominal aorta aneurysm.
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