Company intelligence / Profile preview

Pionyr Immunotherapeutics

South San Francisco, California, United Statespionyrtx.com ↗
Ownership
Private
Development stage
Other
01

Overview

Pionyr’s lead assets PY314 and PY159 are monoclonal antibodies targeting myeloid checkpoints TREM2 and TREM1 respectively. Both completed Phase Ia dose-escalation studies showing safety and tolerability as monotherapy or combined with pembrolizumab. Phase Ib expansion studies were underway for both agents in a range of solid tumor types at the time of acquisition. Early data indicated favorable safety profiles and evidence of immune modulation within the tumor microenvironment.

Therapeutic areas
Oncology
Modalities
Monoclonal antibodies (mAbs)Biologics
Industry
Biotech
02

Partnerships

Gilead Sciences held a minority interest with an exclusive option to acquire Pionyr upon completion of certain milestones; strategic collaboration announced July 2020

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