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Piramed developed small molecule inhibitors targeting the PI3K pathway for oncology and inflammatory diseases. Its lead compound in oncology entered Phase I clinical trials in collaboration with Genentech. The inflammatory disease program was preclinical at the time of Roche’s acquisition. GDC‑0941, a PI3K inhibitor discovered by Piramed, advanced to clinical development under Genentech/Roche. No commercialized products prior to acquisition.
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