Pirch

Pirche is a bioinformatics company specializing in transplant immunology and histocompatibility. The company's core technology, the PIRCHE algorithm, predicts the risk of immune responses in organ and stem cell transplantation by identifying indirectly recognizable HLA epitopes. By analyzing the compatibility of donor and recipient at the epitope level rather than just the antigen level, Pirche helps clinicians minimize the risk of graft rejection and graft-versus-host disease. Beyond transplantation, the platform is utilized in the field of hemophilia to predict the risk of inhibitor formation against Factor VIII treatments. Pirche's services are used globally by transplant centers, clinical laboratories, and pharmaceutical partners to improve patient outcomes through precision matching.