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Pledge Therapeutics uses advanced structure-based drug discovery to develop first-in-class small molecule therapeutics against challenging disease targets. Their initial focus includes antivirals for BK and JC polyomavirus infections in transplant patients. The company has announced preclinical progress on its HHLA2 and IL18BP programs as well as the development of a first antiviral targeting BK virus. No clinical results have been published yet; all lead assets are preclinical.
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