Plenum

Plenum is a San Diego-based biotechnology company developing a next-generation proteomics platform to measure the human proteome at an unprecedented scale and resolution. Founded by veterans from Grail and Illumina, the company integrates proprietary biochemistry, automated hardware, and machine learning to quantify thousands of proteins across large patient cohorts. By mapping protein expression and dynamics, Plenum aims to uncover novel disease biology and identify high-confidence therapeutic targets and biomarkers. The company's technology is designed to overcome the throughput and sensitivity limitations of current proteomic methods, enabling precision medicine applications across a wide range of complex indications.