Company intelligence / Profile preview

Pliant Therapeutics

South San Francisco, California, United Statespliantrx.com ↗
Ownership
Public · PLRX
Development stage
Phase 2
01

Overview

Pliant recently discontinued its Phase 2b/3 BEACON-IPF trial of bexotegrast due to safety concerns, despite showing promising efficacy data regarding forced vital capacity (FVC). The company is now considering future dose-ranging Phase 2b studies with lower bexotegrast doses in pulmonary fibrosis and potentially other non-respiratory indications. The company announced a strategic realignment of its workforce on May 1, 2025, cutting 45% of staff.[7][9]

Therapeutic areas
GastroenterologyPulmonologyOncologyRare DiseasesNeurology
Modalities
Small moleculesmonoclonal antibodies
Industry
Biotech
02

Drug pipeline

14 assets

PLN-101095

1

13 more assets in the full pipeline.

03

Financials

Market cap
$50.5M
Total revenue
$0
Enterprise value
$-78.8M

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