Company intelligence / Profile preview
Pliant Therapeutics
- Ownership
- Public · PLRX
- Development stage
- Phase 2
Overview
Pliant recently discontinued its Phase 2b/3 BEACON-IPF trial of bexotegrast due to safety concerns, despite showing promising efficacy data regarding forced vital capacity (FVC). The company is now considering future dose-ranging Phase 2b studies with lower bexotegrast doses in pulmonary fibrosis and potentially other non-respiratory indications. The company announced a strategic realignment of its workforce on May 1, 2025, cutting 45% of staff.[7][9]
- Therapeutic areas
- GastroenterologyPulmonologyOncologyRare DiseasesNeurology
- Modalities
- Small moleculesmonoclonal antibodies
- Industry
- Biotech
Drug pipeline
14 assets13 more assets in the full pipeline.
Financials
- Market cap
- $50.5M
- Total revenue
- $0
- Enterprise value
- $-78.8M
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