Company intelligence / Profile preview

PolyActiva

Melbourne, Victoria, Australiapolyactiva.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

PolyActiva has demonstrated promising interim Phase 2a results with its lead PA5108 Ocular Implant in patients with mild to moderate glaucoma. The implant delivers latanoprost over six months, achieving >20% intraocular pressure reduction at both three and six months. Repeat dosing was shown to be feasible, with no product-related adverse effects reported. In a separate cohort, clinically meaningful IOP reductions of up to ~35% were observed over a total of nearly one year when two implants were administered sequentially. Most patients did not require additional drop therapy during this period.

Therapeutic areas
OphthalmologyInfectious Diseases
Modalities
Small molecules (delivered via polymeric prodrug ocular implants)Biodegradable drug delivery devices/implants
Industry
Biotech
02

Drug pipeline

5 assets

PA5108 Latanoprost FA SR Ocular Implant

2

4 more assets in the full pipeline.

03

Partnerships

Venture capital partnerships include Brandon Capital’s Medical Research Commercialisation Fund (MRCF)Yuuwa CapitalBiomedical Translation Fund support from Australian government initiatives.

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