Company intelligence / Profile preview

Portola Pharmaceuticals

South San Francisco, California, United Stateslinkedin.com ↗
Ownership
Private
Employees
~324
Development stage
Commercial
01

Overview

Portola developed two FDA-approved drugs:

  • Andexxa® [coagulation factor Xa (recombinant), inactivated], the first antidote for patients treated with rivaroxaban or apixaban who require urgent reversal of anticoagulation due to life-threatening or uncontrolled bleeding.
  • Bevyxxa® (betrixaban), an oral Factor Xa inhibitor for prevention of VTE in acutely ill medical patients.
  • Cerdulatinib was in clinical development for hematologic cancers at time of acquisition. The company was acquired by Alexion Pharmaceuticals in July 2020
Therapeutic areas
OncologyHematologyCardiovascular
Modalities
small moleculesrecombinant proteins (e.g., coagulation factor Xa)monoclonal antibodies
Industry
Biotech
02

Drug pipeline

3 assets

andexanet alfa

Commercial
Indications
Factor Xa inhibitor reversal

2 more assets in the full pipeline.

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03

Partnerships

Novartis (past collaboration on Elinogrel)Millennium Pharmaceuticals, Daiichi Sankyo, Bayer, Janssen, BMS/Pfizer among others

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