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Positivo Biotechnology is developing a novel nonviral, non-integrating DNA gene delivery platform using lipid nanoparticles. Their approach aims to overcome immunogenicity and toxicity issues associated with viral vectors in genetic therapies. The company recently won the 2024 Golden Ticket Award from the Cystic Fibrosis Foundation and Bakar Labs, which provides them with lab space and support to advance their preclinical research in cystic fibrosis. No clinical results have been reported yet as they are still in preclinical development.
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