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Potentia Pharmaceuticals

Crestwood, Kentucky, United Statesbiospace.com ↗
Ownership
Private
Employees
~1
Development stage
Phase 1
01

Overview

Potentia Pharmaceuticals developed the first complement inhibitor for ophthalmological use, targeting age-related macular degeneration. Its lead compound POT‑4 completed a Phase I trial showing safety and tolerability with no serious adverse events. The company’s science supported further clinical development into Phase II trials before its programs were acquired by Apellis Pharmaceuticals.

Therapeutic areas
OphthalmologyHematology
Modalities
Peptide therapeutics (complement inhibitors, specifically compstatin derivatives such as POT-4/APL‑1)
Industry
Biotech
02

Drug pipeline

1 asset

POT-4

Phase 1
Indications
Age-related macular degeneration
03

Partnerships

Alcon—licensed ocular program to Alcon in October 2009 with purchase option agreement for further development of POT–4; partnership ended prior to Apellis acquisition.

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