Company intelligence / Profile preview
Praetego
Durham, North Carolina, United Statespraetego.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
Praetego’s lead candidate PTG‑630 has demonstrated neuroprotection in preclinical models of AD and DPN, showing protection against mild cognitive impairment and biomarker evidence of neuronal benefit. IND-enabling studies are ongoing with an IND filing planned for late 2024. The company has received multiple NIH grants to advance its programs toward clinical trials.
A Phase 2 study will target diabetics with mild cognitive impairment at high risk for AD to demonstrate target engagement and proof of mechanism.
Additional preclinical work supports expansion into diabetic retinopathy as a third indication.
No human clinical results reported yet.- Therapeutic areas
- OphthalmologyEndocrinologyNeurology
- Modalities
- Small molecules (Amadorins)
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
Collaboration with Penn State University on diabetic retinopathy researchCollaboration with University of California at San Diego School of Medicine on CNS diseases
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