Clinical trials
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Phase 3 trials of ulixacaltamide for essential tremor showed significant improvements in activities of daily living scores (4.3 vs 1.7 points placebo); high discontinuation rates noted (35-38%). Phase 2 results positive for vormatrigine in epilepsy (60% seizure reduction) and relutrigine in DEE (seizure-free interval to 67 days).[2][3]
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