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Presage Biosciences developed the CIVO® platform to enable simultaneous evaluation of multiple oncology drugs or combinations directly within patient tumors. The company has completed first-in-human Phase 0 studies demonstrating proof-of-concept for this approach, including recent work with a ROR1-targeting antibody from Pure Biologics. The technology provides detailed molecular profiling and immune response data from real human tumor microenvironments, aiming to accelerate translational oncology research and improve predictive power over traditional preclinical models.
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