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PriZm Therapeutics is advancing SRW101, a synthetic T3 analogue small molecule therapy for MCT8 deficiency/AHDS. SRW101 has shown positive results in compassionate use and emergency IND settings. The company is preparing for a pivotal Phase III registration trial and has received Orphan Drug Designation in the US and EU as well as Rare Pediatric Disease designation. No approved therapies currently exist for this indication.
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