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PAI Life Sciences is a Seattle-based biotechnology company focused on developing vaccines and therapies for neglected tropical diseases. The company's lead program is SchistoShield, a recombinant protein vaccine for schistosomiasis (snail fever) based on the Sm-p80 antigen discovered by Prof. Afzal Siddiqui at Texas Tech University Health Sciences Center. PAI Life Sciences is currently advancing SchistoShield through Phase 1 clinical trials with significant support from the Bill & Melinda Gates Foundation and the National Institutes of Health (NIH). In addition to its work on schistosomiasis, the company is developing vaccine candidates for other global health threats, including leishmaniasis and tuberculosis, and provides specialized adjuvants and translational research services.
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