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Propella Therapeutics is a clinical-stage biotechnology company focused on developing highly selective, next-generation oncology therapeutics. The company utilizes a proprietary medicinal chemistry platform to design drugs with improved safety and efficacy profiles, specifically targeting validated pathways in cancer. Its lead program, CTP-439, is a novel prodrug of abiraterone designed to provide superior pharmacokinetic properties for the treatment of metastatic castration-resistant prostate cancer. In late 2023, Propella was acquired by Roche to bolster its oncology pipeline and leverage Propella's expertise in selective small molecule design.
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