Company intelligence / Profile preview

Protalix BioTherapeutics

Karmiel, Northern District, Israelprotalix.com ↗
Ownership
Public · PLX
Employees
~266
Development stage
Commercial
01

Overview

Protalix has commercialized two enzyme replacement therapies for rare diseases—Elelyso®/Uplyso® for Gaucher disease and Elfabrio® for Fabry disease. Elelyso was the first FDA-approved protein produced in a plant cell-based system. Elfabrio received FDA and EMA approval in May 2023. The company’s pipeline includes PRX–115, a PEGylated uricase for uncontrolled gout that completed a first-in-human study with plans to enter Phase II trials, and PRX–119, a long acting DNase I targeting NETs-related diseases[5][6].

Therapeutic areas
OncologyRare DiseasesRheumatology
Modalities
Recombinant therapeutic proteins (produced in plant cell-based systems)Enzyme replacement therapies
Industry
Biotech
02

Drug pipeline

6 assets

taliglucerase alfa

Approved

5 more assets in the full pipeline.

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03

Partnerships

Pfizer Inc. – global rights to taliglucerase alfa except Brazil[5]Chiesi Farmaceutici S.p.A. – global development/commercialization of Elfabrio[5]
04

Financials

Market cap
$220M
Total revenue
$19.9M
Enterprise value
$188.5M

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