Providence Microbiome Research Center

Providence Microbiome Research Center (PMRC) is an Indian biotechnology and healthcare startup focused on the prevention and treatment of autism spectrum disorder (ASD) and other chronic conditions through gut microbiome modulation. Founded by cardiologist Dr. Chandrashekhar Thodupunuri, the company conducts clinical trials exploring the therapeutic potential of Fecal Microbiota Transplantation (FMT) and targeted antenatal programs. PMRC's lead program is an ICMR-approved clinical trial evaluating FMT for autism to explore its impact on human epigenetics and gut microbiome profiles. Additionally, the company is developing a stool bank and FMT clinics to address inflammatory bowel disease, ulcerative colitis, and Clostridium difficile infections, while researching prenatal interventions like N-acetylcysteine to prevent epigenetic errors during fetal development.