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PRR Therapeutics is an Australian biotechnology company focused on developing first-in-class therapies that target the (Pro)renin Receptor (PRR), also known as ATP6AP2. The company leverages its expertise in the renin-angiotensin system to address diseases driven by PRR-mediated signaling, including various forms of cancer and fibrotic disorders. Their primary focus is on pancreatic cancer, where PRR is overexpressed and promotes tumor growth, and chronic kidney disease, where it drives fibrosis. PRR Therapeutics is advancing a pipeline of peptide-based and small molecule inhibitors designed to block PRR activation and its downstream pathological effects.
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