Company intelligence / Profile preview

Quark Pharmaceuticals

Fremont, California, United Statesen.wikipedia.org ↗
Ownership
Private
Employees
~3
Development stage
Phase 2
01

Overview

Quark Pharmaceuticals was a private biotech company focused on developing RNA interference-based therapies targeting novel genes implicated in chronic and acute diseases. The company leveraged its proprietary BiFAR platform to identify new drug targets. It had collaborations with major pharma companies like Pfizer and academic institutions such as the University at Buffalo. Its clinical pipeline included candidates for hearing loss prevention, cancer therapy through hypoxia pathway modulation, dyslipidemia treatment, and several dermatological conditions. Most recent public information suggests the company ceased operations ("out of business"). Clinical results were not detailed in available sources.

Therapeutic areas
CardiovascularDermatologyOtherOncologyNeurology
Modalities
siRNA (small interfering RNA)RNA interference-based therapeutics
Industry
Biotech
02

Drug pipeline

4 assets

teprasiran

3

3 more assets in the full pipeline.

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03

Partnerships

Pfizer—collaboration/licensing agreement around RTP801-targeting drugs using RNAi technology.Sanwa—licensed phase II compound BT16 for dyslipidemia treatment.University at Buffalo Center for Hearing & Deafness—academic collaboration on chemotherapy-induced hearing loss prevention using SiRNA drugs.

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