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Raft Pharmaceuticals

San Diego, California, United States
Ownership
Private
Development stage
Other
01

Overview

Raft Pharmaceuticals is developing RFT1081, a recombinant protein targeting cholesterol trafficking in lipid rafts of inflamed glia and macrophages, with animal studies showing efficacy in models of chemotherapy- and nerve injury-induced neuropathic pain and migraine. The approach aims to normalize lipid raft microdomains implicated in chronic pain pathology, and recent preclinical data highlight normalization of cholesterol metabolism in spinal microglia as a potential mechanism of action.

Therapeutic areas
Neurology
Modalities
Recombinant proteinProtein
Industry
Biotech
02

Drug pipeline

2 assets

RFT1081

Preclinical

1 more asset in the full pipeline.

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