Company intelligence / Profile preview

Rapa Therapeutics

Rockville  , Maryland, United Statesmassgeneral.org ↗
Ownership
Private
Development stage
Phase 2
01

Overview

Rapa’s lead program RAPA‑501 is an autologous epigenetically reprogrammed TREG/Th2 “hybrid” cell therapy showing safety and biological activity in ALS patients with trends toward slowing pulmonary decline. Their oncology program uses non-genetically engineered rapamycin-resistant Th1/Tc1 cells. Early clinical results include stringent complete remissions in multiple myeloma patients refractory to other treatments. The company’s approach aims to provide less toxic alternatives compared to existing immunotherapies.

Therapeutic areas
OncologyNeurology
Modalities
Autologous T cell therapies (including rapamycin-resistant T cells)Adoptive cell therapyImmunomodulators
Industry
Biotech
02

Drug pipeline

3 assets

RAPA-501

3

2 more assets in the full pipeline.

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03

Partnerships

Supported by TEDCO Venture Funds ($1M investment)collaboration with Sean M. Healey & AMG Center for ALS at Mass General Hospitalpartial support from the ALS Association

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