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RareStone is a Shanghai-based rare disease-focused therapeutics company for the Greater China market. It in-licenses and develops rare disease drugs, including pitolisant (Wakix) for narcolepsy, which has been approved by the China NMPA for excessive daytime sleepiness and cataplexy in adult narcolepsy patients, and setmelanotide (Imcivree) for rare genetic obesity disorders under an exclusive Greater China licensing agreement with Rhythm Pharmaceuticals. The company is commercial or near-commercial in China for pitolisant and is pursuing approvals for setmelanotide and other in-licensed endocrine/rare disease products.[1][4][10]
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