Company intelligence / Profile preview

Redx Pharma

Alderley Park/Macclesfield area near Manchester/Liverpool, Cheshire, United Kingdomredxpharma.com ↗
Ownership
Private
Employees
~74
Development stage
Phase 2
01

Overview

Redx Pharma has advanced multiple small molecule programs into clinical development. Zelasudil (RXC007), a selective ROCK2 inhibitor for fibrotic diseases including idiopathic pulmonary fibrosis, has entered Phase 2 trials. RXC008 targets fibrostenotic Crohn’s disease with completed Phase 1 data presented in early 2025. Zamaporvint (RXC004), a porcupine inhibitor for Wnt-ligand dependent tumors, is also in Phase 2 studies combined with anti-PD‑1 therapy. The pipeline includes additional preclinical assets targeting DDR1 and KRAS.

Therapeutic areas
GastroenterologyOncologyPulmonology
Modalities
Small molecules
Industry
Biotech
02

Drug pipeline

5 assets

zamaporvint

2

4 more assets in the full pipeline.

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03

Partnerships

AstraZeneca – Porcupine inhibitor program AZD5055/RXC006 partnership.Loxo Oncology/Eli Lilly – BTK inhibitor Jaypirca™/pirtobrutinib/LOXO‑305.Jazz Pharmaceuticals – Pan‑RAF inhibitor JZP815 and discovery-stage KRAS program.

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