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Rejuvenate Biomed is a clinical-stage biotech developing AI-designed fixed-dose combinations of existing approved drugs to target multiple aging pathways. Its lead program RJx-01 (galantamine + metformin) has completed a Phase 1b study in older men with cast-induced muscle atrophy, showing safety, tolerability, good bioavailability, and signals of improved strength recovery, leg acceleration, and fatigue resistance versus placebo. A Phase 2 double-blind, placebo-controlled trial in COPD-related sarcopenia is underway, primarily assessing safety and secondarily physical function and muscle strength.[1][6]
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