Company intelligence / Profile preview
Repertoire Immune Medicines
Cambridge, Massachusetts, USArepertoire.com ↗
- Ownership
- Private
- Employees
- ~120
- Development stage
- Phase 1
01
Overview
Repertoire Immune Medicines has advanced a novel multi-clonal T cell therapy into clinical trials for metastatic solid tumors. Its lead program, RPTR‑168, delivers IL‑12 to enhance anti-tumor activity. The company’s DECODE™ platform has demonstrated effectiveness in identifying highly prevalent immunogenic epitopes relevant to both cancer and autoimmunity. Recent partnerships with Genentech and Bristol Myers Squibb validate the breadth of its target discovery capabilities but detailed clinical efficacy results have not yet been published as of May 2025.
- Therapeutic areas
- OncologyImmunologyInfectious Diseases
- Modalities
- T cell therapies (multi-clonal cytokine-enhanced T cells)TCR bispecific moleculesmRNA cancer vaccinesmRNA tolerizing vaccines
- Industry
- Biotech
02
Drug pipeline
17 assets16 more assets in the full pipeline.
03
Partnerships
Genentech/Roche — collaboration on autoimmune disease therapies using DECODE™ platform ($35M upfront + milestones up to $730M)Bristol Myers Squibb — multi-year strategic collaboration on tolerizing vaccines for autoimmunityJDRF T1D Fund — investment/support for type 1 diabetes program
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