Company intelligence / Profile preview

Repertoire Immune Medicines

Cambridge, Massachusetts, USArepertoire.com ↗
Ownership
Private
Employees
~120
Development stage
Phase 1
01

Overview

Repertoire Immune Medicines has advanced a novel multi-clonal T cell therapy into clinical trials for metastatic solid tumors. Its lead program, RPTR‑168, delivers IL‑12 to enhance anti-tumor activity. The company’s DECODE™ platform has demonstrated effectiveness in identifying highly prevalent immunogenic epitopes relevant to both cancer and autoimmunity. Recent partnerships with Genentech and Bristol Myers Squibb validate the breadth of its target discovery capabilities but detailed clinical efficacy results have not yet been published as of May 2025.

Therapeutic areas
OncologyImmunologyInfectious Diseases
Modalities
T cell therapies (multi-clonal cytokine-enhanced T cells)TCR bispecific moleculesmRNA cancer vaccinesmRNA tolerizing vaccines
Industry
Biotech
02

Drug pipeline

17 assets

RPTR-1-201

2

16 more assets in the full pipeline.

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03

Partnerships

Genentech/Roche — collaboration on autoimmune disease therapies using DECODE™ platform ($35M upfront + milestones up to $730M)Bristol Myers Squibb — multi-year strategic collaboration on tolerizing vaccines for autoimmunityJDRF T1D Fund — investment/support for type 1 diabetes program

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