Replenix

Replenix is a premier medical-grade skincare company that specializes in high-performance, antioxidant-based dermatological products. Founded in 1981 and operating as a flagship brand of Topix Pharmaceuticals, the company is renowned for its proprietary Green Tea Polyphenol Technology, which delivers highly purified antioxidants to the skin. Its product portfolio includes clinically-tested treatments for acne, aging, hyperpigmentation, and sensitive skin, featuring medical-grade ingredients such as all-trans-retinol and fractionated hyaluronic acid. Originally available exclusively through physician offices, Replenix expanded to a direct-to-consumer model in 2021 to broaden access to its science-backed skincare solutions. The company maintains vertical integration with in-house R&D and manufacturing facilities in New York.