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Revolution Medicines

Redwood City, California, USArevmed.com ↗

Ownership: Public · RVMD
Employees: ~188
Development stage: Phase 1

Overview

Revolution Medicines’ lead asset RMC‑6236 has advanced to a global Phase 3 trial for metastatic pancreatic ductal adenocarcinoma. In earlier studies, the drug showed encouraging progression-free survival—8.1 months median PFS in second-line patients with KRAS G12X mutations versus historical benchmarks of ~2–3.5 months for chemotherapy. The company’s pipeline includes several other clinical and preclinical mutant-selective RAS inhibitors targeting various solid tumors driven by different KRAS mutations

Therapeutic areas: Oncology
Modalities: Small molecules
Industry: Biotech

Drug pipeline

22 assets

daraxonrasib

Approved

21 more assets in the full pipeline.

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Partnerships

Former partnership with Sanofi on SHP2 program (terminated Dec 2022)Collaboration agreement with Aethon Therapeutics to create therapies for RAS-addicted cancers signed April 2024

Financials

Market cap: $43.2B
Total revenue: $0
Enterprise value: $39.9B

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