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Rhein Biotech was a pioneering biotechnology company specializing in the development and manufacture of recombinant vaccines, most notably for Hepatitis B. The company gained international recognition for its proprietary Hansenula polymorpha yeast-based expression system, which allowed for the cost-effective production of high-quality recombinant proteins. Throughout its history, Rhein Biotech focused on providing affordable vaccine solutions to global markets, particularly in developing nations through partnerships with organizations like UNICEF and the WHO. After a series of mergers and acquisitions, its core technologies and manufacturing capabilities were integrated into larger pharmaceutical entities, eventually becoming part of the Janssen Pharmaceutical Companies of Johnson & Johnson.
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