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River Stone Biotech

Wilmington, Delaware, United Statesriverstonebio.com ↗
Ownership
Private
Development stage
Commercial
01

Overview

River Stone Biotech has developed a proprietary hybrid platform combining synthetic biology and traditional chemistry to produce specialty alkaloid APIs. The company’s lead products—buprenorphine, naloxone, and naltrexone—are approved by global regulatory authorities for opioid use disorder, alcohol use disorder, opioid overdose reversal, and pain. Their process reduces cost and environmental impact compared to traditional methods. The company is expanding its pipeline to include additional "Nal group" compounds[1][2][5][6].

Therapeutic areas
Metabolic DisordersPsychiatryNeurology
Modalities
Small moleculeSynthetic alkaloid (as a subset of small molecules)
Industry
Biotech
02

Drug pipeline

3 assets

buprenorphine

Commercial
Indications
Opioid use disorder, Pain

2 more assets in the full pipeline.

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03

Partnerships

Select global providers for virtual cross-functional operations[2]Open to industry/academic collaborations for generics partnerships[2]

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