Root

Root (often referred to as Root.bio) is a venture-backed biotechnology company focused on precision immunology and the discovery of therapies for autoimmune and inflammatory diseases. Co-founded by Pulitzer Prize-winning author and oncologist Siddhartha Mukherjee and Nathaniel Brooks Horwitz, the company leverages a proprietary platform to map the "root causes" of disease at the cellular and molecular levels. By integrating large-scale biological data with advanced computational models, Root aims to move beyond symptom management toward disease-modifying treatments. The company operates primarily in stealth mode but is recognized as a high-profile player in the emerging field of precision medicine for complex immune-mediated conditions.