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Rottapharm Biotech focuses on innovative drug discovery and development in rheumatology, oncology, pain management, infectious diseases, and advanced therapies. Its lead programs include vorbipiprant (an EP4 antagonist) in Phase I/II trials for metastatic gastrointestinal cancers and CR10049 as a first-in-class kinase inhibitor targeting inflammatory osteoarthritis. The company has also developed a DNA vaccine against COVID‑19 with Takis. Historical strengths include the invention of glucosamine sulfate formulations for osteoarthritis.
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