Company intelligence / Profile preview

Rubicon Biotechnology

Irvine, California, United Statesrubiconbio.com ↗
Ownership
Private
Employees
~7
Development stage
Preclinical
01

Overview

Rubicon Biotechnology develops two proprietary biologic platforms. The first, Fv-Hsp72, delivers heat shock protein Hsp72 into stressed or dying cells to salvage them after acute injuries such as myocardial infarction or traumatic brain injury. The second, a modified form of annexin A5 licensed from MosaMedix B.V., targets phosphatidylserine exposed on the surface of solid tumors and their blood vessels to deliver immunostimulants directly into the tumor microenvironment. Both programs are in preclinical development with collaborations aimed at advancing toward clinical trials. The company has received industry recognition including a Merck Advance Biotech Grant for its work on Fv-Hsp72.

Therapeutic areas
PulmonologyCardiovascularOtherOncologyNeurology
Modalities
Recombinant proteins/biologics (Fv-Hsp72, Modified Annexin A5)Immunostimulants (via Modified Annexin A5)
Industry
Biotech
02

Drug pipeline

2 assets

Fv-Hsp72

Preclinical

1 more asset in the full pipeline.

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03

Partnerships

Celltheon Expression Technologies—for cell line/process development using SMART™ Platform for Fv-Hsp72 program.Merck KGaA—recipient of Merck’s Advance Biotech Grant supporting process development for Fv-Hsp72 program.MosaMedix B.V.—licensor of modified annexin technology used by Rubicon Biotechnology.Collaborations with several leading US research institutions mentioned but not named specifically.

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